You might be eating right, exercising, and still feeling tired, bloated, or stuck with stubborn weight.
What’s happening inside your body could be something far deeper; a slow, silent process called meta-inflammation. Unlike visible inflammation that heals wounds or infections, this type burns quietly within your cells every single day, disturbing your hormones, metabolism, and energy balance.

The good news? Once you understand it, you can stop it.

What Exactly Is Meta-Inflammation?

Meta-inflammation, or metabolic inflammation, is a form of chronic inflammation caused by overnutrition and metabolic overload.
It doesn’t start with infection or injury, it begins when the body keeps receiving more fuel than it can use. This excess energy stresses the cells, especially in the liver, muscles, pancreas, and fat tissue, triggering an immune-like response.

Over time, this ongoing low-grade inflammation quietly sets the stage for diseases like diabetes, obesity, fatty liver, and heart problems, conditions now common in people of all ages.

The Science Behind This Hidden Fire

When mitochondria, the tiny powerhouses of your cells are overloaded with energy, they start leaking free radicals, unstable molecules that damage cell membranes. The immune system mistakes this as a threat and releases inflammatory signals such as TNF-α, IL-6, and CRP.

This cascade disturbs insulin and leptin, two hormones crucial for energy control. As they lose sensitivity, the body stores more fat, increases appetite, and reduces metabolic efficiency.
It’s a vicious loop where more energy intake fuels more inflammation, and that inflammation keeps you craving energy again.

This explains why weight loss stalls or fatigue lingers, even when diet and exercise seem “good enough.”

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https://www.freedomfromdiabetes.org/blog/post/silent-inflammation-ruining-your-health-how-to-stop-it/4930

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